"Nine pro-Iranian fighters, including a leader and a Syrian, were killed and more than 20 wounded in air strikes targeting the villa they were staying in, which served as a communications centre," the Syrian Observatory for Human Rights said.
The Britain-based monitor said it had no word on who carried out the strikes and there was no immediate claim of responsibility.
Israel has carried out hundreds of strikes targeting pro-Iranian groups fighting alongside the forces of President Bashar al-Assad in the country's more than a decade-old civil war.
The United States has carried out a much smaller number of strikes against pro-Iran groups in eastern Syria which it holds responsible for a flurry of attacks on US interests in Iraq and Syria during the Israel-Hamas war in Gaza.
Media close to the Syrian government said the latest strikes were American.
The Observatory said that a few hours earlier, an Iranian cargo plane flew from Damascus to the eastern city of Deir Ezzor carrying technical equipment and soldiers of Iran's Revolutionary Guards.
The villa which was targeted and completely destroyed in the strike had been taken over by the Guards, who are responsible for Iran's foreign operations.
The strikes were the first of their kind in eastern Syria since early February, the Observatory said.
Then, US strikes targeting the eastern cities of Deir Ezzor and Al-Madayeen killed 29 pro-Iran fighters in response to a deadly drone attack on a US base which killed three US soldiers just across the border into Jordan.
Four wounded in Israeli strikes on east Lebanon's Baalbek
Bekaa Valley, Lebanon (AFP) Mar 24, 2024 -
Four people were wounded by Israeli air strikes near Lebanon's eastern city of Baalbek overnight, one of which hit a two-storey building, an AFP correspondent said on Sunday.
Israel and Hamas ally Hezbollah have been exchanging near-daily cross-border fire since the Gaza war erupted in October.
But fears have surged of an all-out conflict in past weeks, with Israel launching air strikes deeper into Lebanese territory, targeting the Baalbek area -- a Hezbollah stronghold -- several times.
The Israeli military said in a statement fighter jets "struck a Hezbollah manufacturing site containing weapons in the area of Baalbek".
The AFP correspondent said the Israeli strikes targeted a Hezbollah centre that had been deserted for some time, wounding four residents in nearby buildings.
"The Israeli air force fired five missiles at a two-storey inhabited building in Al-Osseira, on the outskirts of Baalbek," he said.
The Israeli military also said "approximately 50 launches were identified from Lebanon toward northern Israel, a number of launches were intercepted while the rest fell in open areas".
Hezbollah said it fired "more than 60 Katyusha-type rockets" at two Israeli military positions in the occupied Golan Heights in response to the Israeli strikes.
The strike at Al-Osseira, some 100 kilometres (62 miles) from the Israeli-Lebanese border, ended a period of relative calm that had lasted around 10 days.
Hezbollah began launching near-daily attacks against Israel on October 8 in support of its Palestinian ally Hamas in Gaza and said on Saturday it had carried out several more strikes.
It says it will only end its attacks on Israel if there is a ceasefire in Gaza.
Israeli Defence Minister Yoav Gallant warned in February that a possible truce in Gaza would not affect Israel's "objective" of pushing Hezbollah back from its northern border, by force or diplomacy.
At least 323 people have been killed in Lebanon, most of them Hezbollah fighters, but also at least 56 civilians, according to an AFP count.
At least 10 soldiers and seven civilians have been killed in northern Israel, according to the military.
The exchange of fire, which was initially confined to areas close to the border, has also displaced tens of thousands in southern Lebanon and northern Israel.
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