"An enemy missile hit an open area. Unfortunately, a man and a woman were killed," said city council official Anatoly Kurtev.
Another woman was wounded, he said in a post on Twitter, which is being rebranded as X.
"The shock wave shattered the windows of a very tall building, and damaged an education centre and a supermarket," he said.
Ukrainian media showed images of the aftermath of the attack, including the destroyed frontage of a supermarket with empty shelves that had been plunged into darkness by the blast.
The Ukrainian armed forces said the Russian army had launched "five missiles and carried out 19 air strikes" during the day.
They had fired "multiple rocket launchers 30 times" on Ukrainian positions and inhabited areas.
Ukraine says nine wounded in Russian missile strike in Dnipro
Kyiv, Ukraine (AFP) July 29, 2023 -
A Russian missile struck an apartment block in the central Ukrainian city of Dnipro on Friday, Kyiv officials said, injuring at least nine people including two children.
"Dnipro. Another terrorist attack," said Sergiy Kruk, head of the Ukrainian State Emergency Service, on Telegram.
"Currently, we know of 9 injured, including two children. Work continues."
Internal Affairs Minister Igor Klymenko earlier reported "a Russian strike on a multistorey building in Dnipro", saying five people had been injured.
Videos posted on social media showed smoke billowing from the top floors of a residential building that had been badly damaged.
President Volodymyr Zelensky said: "Dnipro. Friday evening. A high-rise building and the Security Service of Ukraine's building were hit. Russian missile terror again".
"All necessary services are on site... We keep the situation under control. We will do everything to bring Russia to full punishment for aggression and terror against our people."
Russia said on Friday it intercepted two Ukrainian missiles over its southern Rostov region, bordering Ukraine. It said at least a dozen people were wounded by debris falling on the city of Taganrog.
Russian regions bordering Ukraine have seen regular drone strikes and shelling since Moscow launched its military campaign in February last year but have hardly ever been targeted by missiles.
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